Baseline variables

Baumer

Vetel

Hamza

Coffin

Total

Age

41

±16

41

±15

35

±9

43

±15

41

±15

Female %

104

(52.5)

129

(56.8)

29

(40.8)

96

(55.5)

358

(53.5)

Height (m)

1.67

±0.14

1.67

±0.08

1.67

±0.09

1.69

±0.09

1.68

±0.11

Weight (kg)

65.57

±11.47

65.95

±11.93

64.98

±0.09

69.27

±14.53

66.59

±12.00

BMI (kg/m²)

23.10

±3.14

23.58

±3.68

23.46

±2.80

24.29

±4.49

23.61

±3.70

Non-Caucasian ethnicity

(25)

12.6%

(24)

10.6%

(71)

100.0%

(0)

0.0%

(120)

17.9%

Blood in stools

(3)

1.5%

(6)

2.6%

(12)

16.9%

(0)

0.0%

(21)

3.1%

Waterly stool aspect

(182)

91.9%

(195)

85.9%

(59)

83.1%

(173)

100.0%

(609)

91.0%

Work interruption

(87)

44.2%

(90)

39.6%

(0)

%

(66)

39.3%

(243)

41.0%

N of stools last 24 hours

5.05

±1.96

6.01

±2.31

6.34

±2.18

5.85

±2.69

5.72

±2.35

Anal burning

49.0%

44.9%

40.8%

89.6%

57.2%

Anal contractures

19.2%

31.3%

43.7%

91.9%

44.7%

Abdominal pain

88.9%

93.8%

85.9%

94.2%

91.6%

Nausea

68.7%

54.4%

83.1%

66.5%

64.8%

Vomiting

14.2%

8.4%

22.5%

26.5%

26.6%

Appetite loss

79.8%

71.8%

84.5%

80.3%

77.7%

Fatigue

77.8%

81.5%

74.6%

93.1%

82.7%

Insomnia

36.5%

34.4%

49.3%

36.1%

50.0%

Other symptoms

0.0%

0.0%

16.9%

0.0%

1.8%

Pain and palpitation

84.8%

84.1%

64.8%

71.9%

84.3%

Meteorism

75.1%

65.2%

76.1%

91.9%

76.2%

Symptom score baseline

0.73

±0.19

0.71

±0.16

0.87

±0.47

0.75

±0.13

0.74

±0.22

CGI baseline:

-Mild

(27)

13.6%

(39)

17.2%

(7)

9.9%

(60)

34.7%

(133)

19.9%

-Moderate

(131)

66.2%

(157)

69.2%

(39)

54.9%

(49)

28.3%

(376)

56.2%

-Severe

(40)

20.2%

(31)

13.7%

(25)

35.2%

(64)

37.0%

(160)

23.9%

Total

(198)

29.6%

(227)

33.9%

(71)

10.6%

(173)

25.9%

(669)

100.0%